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Question

Biology Question on cell cycle and cell division

Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur ?

A

Chromosomes will be fragmented

B

Chromosomes will not segregate

C

Recombination of chromosome arms will occur

D

Chromosomes will not condense

Answer

Chromosomes will not segregate

Explanation

Solution

Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.