Question
Biology Question on cell cycle and cell division
Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur ?
A
Chromosomes will be fragmented
B
Chromosomes will not segregate
C
Recombination of chromosome arms will occur
D
Chromosomes will not condense
Answer
Chromosomes will not segregate
Explanation
Solution
Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.