Question

Aminoacylation of tRNA is essential for

• A. replication of RNA
• B. formation of peptide bond
• C. splicing
• D. initiation of transcription

Answer 1

Answer: (B)

formation of peptide bond

Answer 2

Aminoacylation of tRNA is the process when tRNAspecific for the amino acidforms aminoacyl. Proteins are synthesized through 3 steps - initiation, elongation, and termination.

• The amino acid is linked to 3' - OH end of tRNA through its -COOH group.
• This process is important for protein synthesis through formation of peptide bonds between amino acids.
• For initiation, the ribosomefirst binds to mRNA at the start codon that is always recognized by the initiator tRNA.
• The amino acids are activated in the presence of ATPand then linked to their tRNA.
• The chargedt t RNA carries the amino acid and binds it to the specific codon on mRNA that codes for that particular amino acid.
• A bond is formed between this amino acid and the one present already.
• The free tRNA is released and is then able to carry another amino acid.

Hence, option B) 'formation of peptide bond' is correct.