Question

Which of the following are correctly matched with their configuration?

• A. (A) 5-membered ring with CN and CH2-NH2 groups
• B. (B) 6-membered ring with CH3 and OH groups
• C. (C) 5-membered ring with COOH and CH3 groups
• D. (D) 6-membered ring with CH3 and CH2OH groups

Answer 1

Answer: (C)

(C) 5-membered ring with COOH and CH3 groups

Answer 2

The explanation for each option requires analyzing the stereochemistry of the chiral centers present in the depicted molecules. For option (C), the chiral center is the carbon atom bonded to the COOH group, the CH3 group, and two different segments of the 5-membered ring. Assigning priorities according to Cahn-Ingold-Prelog rules and determining the configuration (R or S) is necessary. Based on the provided solution, option (C) is the only one correctly matched with its configuration.