Question

Addison's disease is caused due to
A. Hypersecretion of adrenal cortical hormones
B. Hypersecretion of growth hormone
C. Hypersecretion of thymus
D. None of the above

Answer 1

One can state that Addison's disease is a complicated endocrine topic in which the organs do not generate enough steroid hormones. Addison's disease can influence people of all ages; nevertheless, it transpires in people between 30-50 years old as an attitude. Indications by and large gratify progressively and may integrate stomach anguish, inadequacy, and weight reduction.

Complete answer:
Addison's disease, otherwise called adrenal inadequacy, happens when underactive adrenal organs do not create enough hormone cortisol and, at times, the hormone aldosterone. The conceivably dangerous infection influences both genders and can start at any age.
Much of the time, adrenal deficiency results from the adrenal cortex's pulverization, the external layer of the adrenal organs. This problem is known as essential adrenal inadequacy. It is generally an immune system condition in which a patient's insusceptible framework utilizes its antibodies to assault and decimate its adrenal organs. Causes of essential adrenal inadequacy include tuberculosis, adrenal tumors, and other infections.
Secondary adrenal inadequacy is a more familiar type of adrenal deficiency because of an absence of adrenocorticotropin (ACTH). ACTH is a hormone emitted by the pituitary organ, which, this way, animates the adrenal organs to deliver cortisol, however not aldosterone.
So, the correct answer is “Option A”.

Additional Information:
Hypersecretion of growth hormone can cause gigantism in kids, where their bones and their body grow excessively. It can cause acromegaly in grown-ups, which makes the hands, feet, and face bigger than ordinary.
Myasthenia gravis happens when the thymus is enormous and produces antibodies that obstruct or crush the muscles' receptor locales.

Note: Essential adrenal cortical deficiency is a moderately uncommon issue otherwise called Addison disease. It happens when the adrenal cortex layers are devastated via immune system problems, tuberculosis, metastatic carcinomas, drain, contaminations, poisons, or certain drugs. Auxiliary adrenal inadequacy might be brought about by hypopituitarism, careful expulsion of the pituitary organ, or unexpected discontinuance of long haul, high-portion glucocorticoid treatment. Issues with the nerve center bring about tertiary adrenal inadequacy.