Question

According to the compatibility of antigen and antibody, select the correct pair
A. Antigen B and Antibody B
B. Antigen A and Antibody B
C. Antibody A and Antigen B
D. Both B and C

Answer 1

In humans, the presence of antigens on the surface of the red blood cells determines the blood group of the person. The surface of the RBC might possess antigen A, antigen B, both or none. The antibody corresponding to the surface antigen is absent from the blood serum of that person and the antigen corresponding to the antibody should not be present on the cell surface.

Complete answer:
According to the compatibility of antigen and antibody, the correct pairs are:

Antigen A and antibody B
Antibody A and antigen B
The method of determining and assigning blood groups is done through the process of ABO blood grouping.
Some of the important points regarding the concept are:
If the surface antigen on the RBC is A, then the serum would contain antibody B. The blood group of the person would be A.
If the surface antigen on the RBC is B, then the serum would contain antibody A. The blood group of the person would be B.
If both antigens A and B are present on the cell surface, the serum would contain neither antibody A nor B. The blood group would be AB.
If both antigens A and B are absent from the cell surface, the serum would contain both antibodies A and B. The blood group would be O.

The correct answer is an option ( D ) that is Both B and C.

Note:
A person with blood group AB can receive the blood of any group, hence he/she is referred to as Universal Recipient. A person with blood group O can donate blood to a person with any blood group, hence he/she is referred to as Universal Donor.
Transfusion between incompatible donor and recipient can lead to complications like clogging of blood vessels.