Question
Pharmacology Question on General Pharmacology
According to lipinski's rule of 5, which of the following properties of drug molecules are likely to cause poor oral absorption
A
A molecular weight lesser than 500
B
A log P less than 5
C
Less than 5 hydrogen bond donors
D
More than 10 hydrogen bond accepters
Answer
More than 10 hydrogen bond accepters
Explanation
Solution
The correct option is (D) : More than 10 hydrogen bond accepters