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Question

Physiology Question on The respiratory system

35-year-old woman with a long history of dyspnea, chronic cough, sputum production, and wheezing dies of respiratory failure following a bout of lobar pneumonia. She was not a smoker or an alcoholic. The lung autopsy is shown in the image. Which of the following underlying condition was most likely associated with the pathologic changes shown here ?dyspnea

A

Mutation in dynein arms

B

Cystic fibrosis

C

Alpha 1 antitrypsin deficiency

D

Antibodies against type 4 collagen

Answer

Alpha 1 antitrypsin deficiency

Explanation

Solution

The correct option is (C): Alpha 1 antitrypsin deficiency.